Ace the Ambulatory Care Nurse Exam 2025 – Blaze Your Trail in Healthcare!

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Which of the following complaints would most likely indicate a side effect of loop diuretics?

Fatigue

Nausea

Dizziness

All of the above

Loop diuretics, such as furosemide, are commonly used to manage conditions like heart failure and edema by promoting diuresis (increased urine production). While they are effective in relieving fluid overload, they can also lead to several side effects due to their mechanism of action and the changes they induce in electrolyte balance.

Fatigue is a notable side effect of loop diuretics. As these medications increase fluid loss, they can cause dehydration and subsequent electrolyte imbalances, particularly a reduction in potassium levels (hypokalemia), which can lead to feelings of weakness or fatigue.

Nausea can occur as a digestive response to the changes in fluid and electrolyte balance, or as a result of rapid diuresis affecting overall body homeostasis. If the body is experiencing significant shifts in hydration status, this can lead to gastrointestinal disturbances, including nausea.

Dizziness is another potential side effect. Loop diuretics can lead to a drop in blood pressure, particularly when standing up (orthostatic hypotension), which can manifest as dizziness or lightheadedness. The increased excretion of water and electrolytes can also contribute to these feelings, especially if dehydration is a concern.

In conclusion, all the listed complaints—fatigue, nausea, and

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